From the Front Lines of Genomics

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DRAGEN Uncovers Gold in PrecisionFDA Hidden Treasures – Warm Up Challenge

Oct. 2017

At Festival of Genomics Boston on Oct. 4, 2017, PrecisionFDA announced the results of its latest challenge, of which there were 86 valid entries from 30 participants. Out of the 86 entries, 45 found all 50 injected variants. Among entries catching all 50 injected variants, Edico Genome’s DRAGEN V2 Germline Pipeline won five of the six accuracy metrics:  SNP recall and SNP F-score, and indel precision, indel recall and indel F-score, and placed second on the sixth metric (SNP precision). Through all aspects of the challenge, DRAGEN emerged as a top player, receiving Warm Up in silico Variant Catchers and Warm Up in silico VAF Spotters badges on most submissions.

Uncorking The Big Data Bottleneck with FPGAs

June 2017

The next-generation sequencing (NGS) industry is set to become one of the largest producers of data by 2025, raising the question: How can we process and store such vast amounts of data? The void between Moore’s Law, which states CPU capabilities will double every two years, and the projected doubling of genomic data every seven months creates a constraining bottleneck for the entire genomic testing industry.

As an alternative to traditionally used CPU-based systems, FPGAs (Field-Programable Gate Array) are able to process genomic data at much quicker speeds, enabling institutes to keep up with high throughput demands.

Edico Genome’s DRAGEN™ (Dynamic Read Analysis for Genomics) Bio-IT Platform leverages FPGA technology to provide customers with hardware-accelerated implementation of genome pipeline algorithms.

Bio-IT 2017: Customer Recognition in the Best Practices Awards

June 2, 2017

Guest post from Pieter van Rooyen, CEO and Founder of Edico Genome

We’re back from Bio-IT World in Boston and excited to share recognition of our customers Earlham Institute and Rady Children’s Institute of Genomic Medicine. Our mission at Edico Genome is to propel our customers to make an impact in their fields. We want to enable our customers anywhere from sustaining crops with agriculture to aiding in diagnosis with clinical genomics. Their work is an integral part of why we do what we do.

Recorded Webinar: The Future of Pediatric Genomics

May 23, 2017

On Tuesday, May 16th we hosted a webinar about the future of pediatric medicine together with the Rady Children’s Institute for Genomic Medicine. Dr. David Dimmock, Medical Director for the Institute for Genomic Medicine, joined our CEO, Pieter van Rooyen, to discuss how the “ultra-rapid method” has been implemented at the Rady Children’s Institute for Genomic Medicine and what the team there has been able to accomplish with this innovative infrastructure enabling rapid NGS data analysis, disease diagnosis and treatment.

Why the need for an ultra-rapid diagnostics test? There are over 8,000 genetic diseases and collectively they represent the leading cause of death in infants in NICU and PICU. Quick diagnoses and a plan of action that eliminates any guess work involved in diagnosis and optimal treatment saves lives, as has been evidenced at Rady.

The ultra-rapid method was recently deployed to the NICU and PICU at the Rady Children’s Institute and has already been hugely successful.

“60-80% (of children at Rady) that we make a diagnostic on, we actually make a change to treatment of that child,” said Dr. David Dimmock.

What does the ultra-rapid method look like at Rady? What have been some of the triumphs and challenges? How do we scale this infrastructure to other children’s hospitals?

You can watch the recorded webinar here:

DRAGEN is Now Available on Amazon Web Services’ FPGA-Enabled Cloud Instances

April 10, 2017

Guest Post by Rami Mehio, VP of Engineering at Edico Genome

Today at AWS Summit San Francisco, Dr. Werner Vogels, Chief Technology Officer at, announced the general availability of their F1 instance. These EC2 F1 instances, Field Programmable Gate Array (FPGA)-enabled instances in the cloud, are top of the line. They include extremely powerful Xilinx FPGAs. The launch of FPGA-enabled F1 instances on AWS means exciting updates for genomics cloud-users! The F1 instance enables us to further optimize DRAGEN to near real-time data analysis. It also allows us to deploy highly advanced and computationally intensive algorithms, enabling DRAGEN to deliver unprecedented speed, accuracy and overall performance.

The San Diego Daily Transcript: Leading Startups/New Businesses

April 10, 2017

“Along with its great weather, military presence and world-famous zoo, San Diego is known for its innovative minds. Many work in relative obscurity, tolling away on some new technology that may make our lives easier or provide a boost to the local economy.”

Edico Genome is featured in the San Diego Daily Transcript’s “Leading Startups in San Diego” issue.

Read: Leading Startups in San Diego

Front Line Genomics Ebook

Clinical Genomics 101: An Introduction to Clinical Genomics 2017 Edition

March 23, 2017

Front Line Genomics recently published their 2017 version of Clinical Genomics 101. The e-book is a guide designed to introduce readers to the practical and legal complications of genomics, from collecting samples and setting up workflows to analyzing results and on a broader scale, the potential of genomics in healthcare.

Edico Genome’s technology is featured on page 48 of the e-book.

White Paper Feature: Precision Medicine for Newborns by 26-Hour Whole Genome Sequencing

March 22, 2017

Did you know that over 20% of infant deaths are caused by genetic illnesses. Further, did you know that up to 1/3 of admissions to neonatal intensive care are caused by genetic illnesses? Genetic diseases and congenital anomalies are the leading cause of death in infants in the United States, especially in Neonatal Intensive Care Units (NICU) and Pediatric Intensive Care Units (PICU). Together with the Rady Children’s Institute for Genomic Medicine, led by Dr. Stephen Kingsmore, we’ve developed a scalable technical solution to address these troubling statistics.

From the Front Lines of Genomic Medicine

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