Edico Genome’s DRAGEN Bio-IT Processor Now Broadly Available to Customers
Rapid Analysis of Next-Generation Sequencing Data to be Demonstrated at the American Society of Human Genetics (ASHG) 2014 Annual Meeting
SAN DIEGO, Oct. 13, 2014 – Edico Genome today announced the DRAGEN™ Bio-IT Processor, the world’s first bioinformatics application-specific integrated circuit (ASIC), which is embedded on a PCIe form factor card and accompanied with software as a Platform-as-a-Service (PaaS), is now broadly available to clinical labs and researchers utilizing next-generation sequencing instruments. The impact of the speed and compact size of DRAGEN will be demonstrated at the American Society of Human Genetics 2014 Annual Meeting, taking place Oct. 18-22 in San Diego. Results from a study conducted with Sequenom Laboratories, a recent customer, comparing results between Sequenom Laboratories’ current analysis pipeline and the results using DRAGEN, will also be presented.
“My team’s use of the DRAGEN processor has enabled us to analyze our RNA-seq data more than 60 fold faster than a 16-core CPU, shortening analysis times from 12 minutes down to 11 seconds per RNA-seq dataset, with equivalent accuracy as compared to standard software,” said Gene Yeo, Ph.D., Associate Professor, Department of Cellular and Molecular Medicine and Institute for Genomic Medicine, University of California San Diego. “As a result, we have now integrated DRAGEN into use at the San Diego Supercomputer Center, enabling UCSD labs and San Diego-based research institutions to benefit from the speed and accuracy of the card as well.”
Added Pieter van Rooyen, Ph.D., Chief Executive Officer of Edico Genome, “The impact of DRAGEN’s ability to rapidly and accurately analyze data in a cost-effective manner is greatly magnified when analyzing massive data sets, such as whole genomes, or large numbers of smaller tests, such as RNA-seq. Due to these advantages, we’ve already had a tremendous response to DRAGEN’s early access program, and now we are able to make our bio-IT processor broadly available to companies and academic institutions with low- to very high-volume sequencing capacities. We see particular benefits for using DRAGEN for applications such as guiding cancer treatment, conducting non-invasive prenatal testing and diagnosing rare diseases. ”
The results of Sequenom Laboratories’ analysis will be presented at ASHG on Monday, Oct. 20, from 2:00-3:00 p.m. PT in the Bioinformatics and Genomic Technology session (1675M). Also at ASHG, Edico will be holding a drawing for a DRAGEN card with two years of mid-tier service. Institutions performing either research or clinical sequencing are encouraged to visit Edico’s booth 632 or apply online between Oct. 18-21 at edicogenome.com/early-access to enter the drawing and for contest rules and details. Developments can be followed via #EntertheDRAGEN or visiting @EdicoGenome. (No purchase or payment necessary. Void where prohibited).
Edico Genome’s DRAGEN Bio-IT Processor reduces the computational time required for analyzing a whole human genome from 24 hours down to 18 minutes. The company has demonstrated how one DRAGEN accelerator card can be used to analyze the data generated by a full HiSeq X Ten system producing 18,000 whole human genomes per year, which otherwise would take over 50 high-end computer servers. It is estimated this can result in a savings of approximately $6 million over four years. This approach reduces the need for clusters of large servers to process the data, reducing costs related to storage space and IT infrastructure. Edico Genome has completed validation studies with lead customers that include clinical labs and sequencing centers and has submitted this data for publication by peer-reviewed journals.
DRAGEN can be integrated into sequencing machines and next-generation sequencing bioinformatics servers. The processor is loaded with highly optimized algorithms for mapping, alignment, sorting and variant calling. Interested parties may learn more about the technology by visiting www.edicogenome.com/dragen/or visiting www.youtube.com/watch?v=TXcrErjf3x8 to view a video of Eric Topol, M.D., professor of genomics at Scripps Research Institute and Dr. van Rooyen discussing the DRAGEN chip in more detail.
Sequenom Laboratories is a wholly-owned subsidiary of Sequenom, Inc.
About Edico Genome
Edico Genome has developed the DRAGEN™ Bio-IT Processor, the world’s first next-generation sequencing bioinformatics application-specific integrated circuit (ASIC), which is embedded on a PCIe form factor card and accompanied with software as a Platform-as-a-Service (PaaS) platform. This chip is able to analyze the large amounts of data generated by next-generation sequencing rapidly and cost effectively, without compromising accuracy, and overcoming a key bottleneck in the DNA sequencing workflow. The company is a member of EvoNexus,San Diego’s only community-supported, fully pro-bono technology incubator. For more information, visit www.EdicoGenome.com.