The DRAGEN Complete Suite (CS) is a comprehensive solution that offers the industry-leading speeds of DRAGEN with the full collection of DRAGEN pipelines. The DRAGEN CS is available on the cloud with enhanced features, such as BCL conversion and data streaming, for even faster analysis times.
DRAGEN CS includes second-generation versions of the DRAGEN germline and somatic pipelines, which feature improved mapping and aligning algorithms and a new sample prep and sequencing error correction algorithm. The new algorithms significantly improve variant-calling accuracy, particularly for insertions and deletions (INDELs).
The DRAGEN Germline V2 Pipeline was a top performer in the PrecisionFDA Hidden Treasures – Warm Up Challenge in October 2017, receiving the top score in five of six accuracy metrics amongst entries catching all 50 injected variants.
DRAGEN CS contains tools for all pipeline steps, including mapping/aligning, position sorting, duplicate marking, and variant calling. The application accepts sequencing data inputs in BCL, FASTQ, and BAM/CRAM formats, and features BCL conversion, download and upload streaming, and compressed hash tables for a more streamlined and efficient workflow.