DRAGEN on Seven Bridges

Edico Genome’s DRAGEN Secondary Analysis Solutions Now Available Via Seven Bridges

DRAGEN’s Germline, Somatic and RNA Gene Fusion Detection Pipelines are now commercially available on Seven Bridges, enabling new and existing Seven Bridges’ customers to leverage DRAGEN’s ultra rapid speeds and accuracy.

The DRAGEN suite of pipelines deliver industry leading speeds and scalability. In contrast to 20 to 30 hours using traditional technologies, such as BWA-GATK, DRAGEN is able to analyze a whole human genome at 30x coverage in approximately 20 minutes. The DRAGEN suite of applications on Seven Bridges is enabled through Amazon Web Services’ (AWS) EC2 F1 Instances, allowing DRAGEN in the cloud to achieve the same industry leading speeds as its onsite solution without the upfront investment costs.

For technical support or additional information about DRAGEN on Seven Bridges, click here.

Available Pipelines

DRAGEN Germline V2 Pipeline

DRAGEN’s Germline V2 Pipeline is now available in AWS Marketplace. The DRAGEN Germline V2 Pipeline enables ultra-rapid analysis of Next Generation Sequencing (NGS) data, accelerating analysis time from many hours, with pipelines including BWA+GATK or Isaac, to minutes, while also improving accuracy for both SNPs and INDELs.

DRAGEN Somatic V2 Pipeline

The DRAGEN Somatic V2 Pipeline includes tumor-only and tumor/normal modes, designed for use in detecting somatic variants present in tumor samples.

DRAGEN RNA Gene Fusion Pipeline

The DRAGEN RNA Gene Fusion Pipeline performs transcriptome analysis starting with splice junction discovery and alignment, followed by gene fusion detection.

Ultra-Rapid Genomics Cloud

Edico Genome’s DRAGEN Bio-IT Platform is deployed on Amazon Web Services’ Elastic Compute Cloud (EC2) F1 instances, a compute instance with field programmable gate arrays (FPGAs) which can be programmed to create custom hardware accelerations.

A cloud configuration provides users with the flexibility to scale up to the cloud during times of high capacity and return to onsite analysis when demand is reduced. The platform is compliant with the Health Insurance Portability and Accountability Act, regulations developed by the U.S. Department of Health and Human Services to protect the privacy and security of patients’ health information. Onsite analysis is also feasible, with both systems managed through the DRAGEN web portal, featuring an easy-to-use graphical user interface. Pipelines are identical whether executed in the cloud or onsite.

Seven Bridges

Seven Bridges is a leading biomedical data company and specializes in software and data analytics that help researchers turn raw genomic and clinical data into actionable results. Its data ecosystem is used by thousands of researchers in biotech, pharmaceutical, and academic labs, as well as some of the world’s largest national genomics research programs, including those led by the National Institutes of Health, Genomics England, and the U.S. Department of Veterans Affairs.